Ipamorelin and CJC-1295 (without DAC) are two popular peptides used together for their synergistic effects on growth hormone release. Ipamorelin is a selective ghrelin receptor agonist that stimulates the pituitary to secrete growth hormone, while CJC-1295 without DAC (also known as CJC-1295 free acid or CJC-1295-Phe) is an analog of GHRH that prolongs the half-life of endogenous GH. When combined, they produce a robust and sustained increase in circulating growth hormone and IGF-1 levels, which can aid muscle growth, fat loss, recovery, and anti-aging.

Dosage Guidelines
-----------------
The typical dosing protocol for ipamorelin plus CJC-1295 free acid is based on weight, training intensity, and desired outcomes. A common regimen involves:

• Ipamorelin: 100–200 micrograms per injection.


• CJC-1295 (free acid): 250–500 micrograms per injection.

The injections are usually administered subcutaneously into the abdomen or thigh. The most common schedule is twice daily, once in the morning and again before bed, to mimic the natural pulsatile secretion of growth hormone. Some users prefer a single dose at night, especially when using CJC-1295 free acid alone; however, pairing it with ipamorelin tends to be more effective.

Cycle Length
------------
A typical cycle lasts 8–12 weeks. After completion, a drug holiday of 4–6 weeks is recommended before starting another cycle. This helps prevent receptor downregulation and allows the body’s natural GH axis to recover.

Stacking with Other Peptides or Hormones
----------------------------------------
Many athletes stack ipamorelin/CJC-1295 with other peptides for enhanced results:

• Growth Hormone Secretagogues: Sermorelin, Tesamorelin, or Hexarelin can be added to increase the GH pulse amplitude.


• IGF-1 LR3 or IGF-1 DES: Directly increases IGF-1 levels; useful when rapid muscle gains are desired.


• Melanotan II or Melanotan I: For skin tone improvements and increased appetite.


• AOD-9604: A fragment of GH that promotes fat loss without stimulating GH directly.

These combinations should be approached cautiously, as the cumulative effect on GH can be significant. It is advisable to monitor IGF-1 levels every 2–3 weeks during a cycle.

Monitoring and Side Effects
---------------------------
Regular blood tests are essential to track IGF-1, testosterone, thyroid function, and liver enzymes. Common side effects include water retention, mild headaches, tingling sensations, or increased appetite. Rarely, users may experience elevated triglycerides or insulin resistance; these can be mitigated by maintaining a balanced diet and regular exercise.

Safety Precautions
------------------

• Sterility: Use sterile needles and syringes for each injection to avoid contamination.


• Dosage Accuracy: Calibrate your syringe properly; many people misread the microgram scale, leading to overdosing or underdosing.


• Pregnancy & Breastfeeding: Avoid use during pregnancy or while nursing as safety data are lacking.

Related Products

----------------
Several manufacturers produce high-quality ipamorelin and CJC-1295 free acid:

1. Peptide Institute (PI) – Known for rigorous purity testing, PI offers both peptides in 100 mg vials with a 30 µg/ml concentration.


2. Proven Peptides – Provides bulk peptide powder with detailed dosage instructions and a quick-delivery option for international clients.


3. Bio-Techne (formerly Sigma-Aldrich) – Supplies research-grade peptides that are commonly used by laboratories and clinical settings; they also offer certified reference materials for quality control.


4. PCT Peptides – Offers ready-to-use solutions with pre-measured doses, ideal for beginners who want a hassle-free experience.


5. Synthesis Pharma – Specializes in custom peptide synthesis, allowing users to tweak the amino acid sequence if desired.

Each of these brands has its own storage requirements; most require refrigeration at 2–8 °C and should be kept away from light. Once thawed, they can generally be stored for up to two weeks on a cool surface before use.

Administration Tips
-------------------

• Mixing: Dissolve the peptide powder in sterile water or saline, vortex gently, then aliquot into pre-filled syringes.


• Injection Site Rotation: Rotate injection sites daily to avoid lipodystrophy and ensure consistent absorption.


• Timing with Meals: Inject on an empty stomach for optimal absorption; however, some users prefer post-meal injections to reduce gastrointestinal discomfort.

Aftercare

---------
Post-injection, a light massage at the site can help disperse the peptide into the tissue. Hydration is key—drink 500–750 ml of water after each injection to aid in circulation and mitigate mild swelling.

Conclusion
----------
Combining ipamorelin with CJC-1295 free acid offers a potent means of stimulating endogenous growth hormone production, leading to improved muscle mass, fat loss, and valley overall vitality. By adhering to recommended dosages, monitoring blood markers, and using reputable peptide suppliers, users can maximize benefits while minimizing risks. Always consider consulting a healthcare professional before beginning any peptide protocol, especially if you have underlying medical conditions or are taking other medications.